Endocrine Abstracts

Introduction: Primary aldosteronism (PA) is an important cause of hypertension. Adrenal hyperplasia (AH) and aldosterone-producing adrenocortical adenoma (APA) are considered the most frequent causes of PA. Histopathological analysis of unilateral PA has been difficult since no clear morphological criteria existed for defining aldosterone-producing cells. Recently, the distribution of adrenal cells forming aldosterone and cortisol has been studied by using specific monoclonal ...